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KMID : 0613820060160071174
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Journal of Life Science
2006 Volume.16 No. 7 p.1174 ~ p.1180
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Effect of a Combination of Mental Activity with Experimental Subway Noise on Hematology.
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Choi Seok-Cheol
Hyun Kyung-Yae
Park Jae-Hyun
Kwon Heun-Young
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Abstract
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The present study was sought to clarify whether the combination of mental activity with subway noise affects hematological variables. Fifty-six healthy volunteers participated in this experiment and underwent a stress task consisting of combination of mental activity (mental arithmetic) with subway noise for 50 min and 60 min of recovery after the end of the stress task. Venous blood samples were collected for measuring CBC, prothrombin time (PT), activated partial thromboplastin time (aPTT), erythrocyte sedimentation rate (ESR), fibrinogen concentration, D-dimer and high sensitive C-reactive protein (H-CRP) levels before (baseline), 50 min of stress task (S-50m), and 60 min of recovery (R-60m). Total leukocyte, neutrophil and lymphocyte counts significantly increased at R-60m compared with baselines. RBC count at S-50m was higher, while monocyte counts at S-50m and R-60m were lower than those of baselines. aPTTs shortened at S-50m and R-60m, but PT reduced at R-60m as compared with baselines. D-dimer and H-CRP levels at S-50m and R-60m were significantly higher than those of baselines. These findings imply that a combination of mental activity with subway noise may cause leukocytosis, hemoconcentration, shortened PT and aPTT, decreased ESR, and raised D-dimer and H-CRP levels, suggesting possible development of inflammation and prothrombogenic reaction attributable to a subway environment.
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KEYWORD
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Mental activity, subway noise, stress, hematology
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